A functional mTORC1 signaling is indispensable for c-Myc driven hepatocarcinogenesis

Amplification and/or activation of the c-Myc protooncogene is one of the leading genetic events along hepatocarcinogenesis. The oncogenic potential of c-Myc has been proven experimentally by the finding that its overexpression in the mouse liver triggers tumor formation. However, the molecular mecha...

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Detaylı Bibliyografya
Yayımlandı:Hepatology
Asıl Yazarlar: Liu, Pin, Ge, Mengmeng, Hu, Junjie, Li, Xiaolei, Che, Li, Sun, Kun, Cheng, Lili, Huang, Yuedong, Pilo, Maria G., Cigliano, Antonio, Pes, Giovanni M., Pascale, Rosa M., Brozzetti, Stefania, Vidili, Gianpaolo, Porcu, Alberto, Cossu, Antonio, Palmieri, Giuseppe, Sini, Maria C., Ribback, Silvia, Dombrowski, Frank, Tao, Junyan, Calvisi, Diego F., Chen, Ligong, Chen, Xin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481473/
https://ncbi.nlm.nih.gov/pubmed/28370287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29183
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