Nm23-H1 Metastasis Suppressor Expression Level Influences the Binding Properties, Stability, and Function of the Kinase Suppressor of Ras1 (KSR1) Erk Scaffold in Breast Carcinoma Cells

Metastatic disease is a significant contributor to cancer patient mortality. We previously reported that the Kinase Suppressor of Ras1 (KSR1) scaffold protein for the Erk mitogen-activated protein kinase pathway coimmunoprecipitated the metastasis suppressor protein Nm23-H1. We now hypothesize that...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Salerno, Massimiliano, Palmieri, Diane, Bouadis, Amina, Halverson, Douglas, Steeg, Patricia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15684389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.4.1379-1388.2005
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