Nm23-H1 Metastasis Suppressor Expression Level Influences the Binding Properties, Stability, and Function of the Kinase Suppressor of Ras1 (KSR1) Erk Scaffold in Breast Carcinoma Cells

Metastatic disease is a significant contributor to cancer patient mortality. We previously reported that the Kinase Suppressor of Ras1 (KSR1) scaffold protein for the Erk mitogen-activated protein kinase pathway coimmunoprecipitated the metastasis suppressor protein Nm23-H1. We now hypothesize that...

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Autors principals: Salerno, Massimiliano, Palmieri, Diane, Bouadis, Amina, Halverson, Douglas, Steeg, Patricia S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC548014/
https://ncbi.nlm.nih.gov/pubmed/15684389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.4.1379-1388.2005
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