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Kinase suppressor of Ras 1 (KSR1) is required for full ERK activation in thymocytes but not for thymocyte selection
The scaffold protein kinase suppressor of Ras 1 (KSR1) is critical for efficient activation of ERK in a number of cell types. Consistent with this, we observed a defect in ERK activation in thymocytes that lack KSR1. Interestingly, we found that the defect was much greater after PMA stimulation than...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976810/ https://ncbi.nlm.nih.gov/pubmed/20865788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040349 |
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