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Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase
The genetic code is established in aminoacylation reactions catalyzed by aminoacyl-tRNA synthetases. Many aminoacyl-tRNA synthetases require an additional domain for editing, to correct errors made by the catalytic domain. A nonfunctional editing domain results in an ambiguous genetic code, where a...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547871/ https://ncbi.nlm.nih.gov/pubmed/15647356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409064102 |
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