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An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS response
Mistranslation in bacterial and mammalian cells leads to production of statistical proteins that are, in turn, associated with specific cell or animal pathologies, including death of bacterial cells, apoptosis of mammalian cells in culture, and neurodegeneration in the mouse. A major source of mistr...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1794292/ https://ncbi.nlm.nih.gov/pubmed/17264207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610835104 |
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