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Aminoacyl tRNA synthetases and their connections to disease
Aminoacylation of transfer RNAs establishes the rules of the genetic code. The reactions are catalyzed by an ancient group of 20 enzymes (one for each amino acid) known as aminoacyl tRNA synthetases (AARSs). Surprisingly, the etiology of specific diseases—including cancer, neuronal pathologies, auto...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516211/ https://ncbi.nlm.nih.gov/pubmed/18682559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802862105 |
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