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p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish
Brain and heart pathologies are caused by editing defects of transfer RNA (tRNA) synthetases, which preserve genetic code fidelity by removing incorrect amino acids misattached to tRNAs. To extend understanding of the broader impact of synthetase editing reactions on organismal homeostasis, and base...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968768/ https://ncbi.nlm.nih.gov/pubmed/27402763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608139113 |
| Oznake: |
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