p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish

Brain and heart pathologies are caused by editing defects of transfer RNA (tRNA) synthetases, which preserve genetic code fidelity by removing incorrect amino acids misattached to tRNAs. To extend understanding of the broader impact of synthetase editing reactions on organismal homeostasis, and base...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Song, Youngzee, Shi, Yi, Carland, Tristan M., Lian, Shanshan, Sasaki, Tomoyuki, Schork, Nicholas J., Head, Steven R., Kishi, Shuji, Schimmel, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968768/
https://ncbi.nlm.nih.gov/pubmed/27402763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608139113
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky