Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy

Misfolded proteins are an emerging hallmark of cardiac diseases. Although some misfolded proteins, such as desmin, are associated with mutations in the genes encoding these disease-associated proteins, little is known regarding more general mechanisms that contribute to the generation of misfolded p...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Liu, Ye, Satz, Jakob S., Vo, My-Nuong, Nangle, Leslie A., Schimmel, Paul, Ackerman, Susan L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267364/
https://ncbi.nlm.nih.gov/pubmed/25422440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420196111
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