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Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy

Misfolded proteins are an emerging hallmark of cardiac diseases. Although some misfolded proteins, such as desmin, are associated with mutations in the genes encoding these disease-associated proteins, little is known regarding more general mechanisms that contribute to the generation of misfolded p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liu, Ye, Satz, Jakob S., Vo, My-Nuong, Nangle, Leslie A., Schimmel, Paul, Ackerman, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267364/
https://ncbi.nlm.nih.gov/pubmed/25422440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420196111
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