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Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy
Misfolded proteins are an emerging hallmark of cardiac diseases. Although some misfolded proteins, such as desmin, are associated with mutations in the genes encoding these disease-associated proteins, little is known regarding more general mechanisms that contribute to the generation of misfolded p...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267364/ https://ncbi.nlm.nih.gov/pubmed/25422440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420196111 |
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