Identification and preliminary characterization of protein-cysteine farnesyltransferase.

Ras proteins must be isoprenylated at a conserved cysteine residue near the carboxyl terminus (Cys-186 in mammalian Ras p21 proteins) in order to exert their biological activity. Previous studies indicate that an intermediate in the mevalonate pathway, most likely farnesyl pyrophosphate, is the dono...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Manne, V, Roberts, D, Tobin, A, O'Rourke, E, De Virgilio, M, Meyers, C, Ahmed, N, Kurz, B, Resh, M, Kung, H F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54783/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2217184/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7541
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!