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In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PML.

Acute promyelocytic leukemia (APL) has been ascribed to a chromosomal translocation event which results in a fusion protein comprising the PML protein and retinoic acid receptor alpha. PML is normally a component of a nuclear multiprotein complex which is disrupted in the APL disease state. Here, tw...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Borden, K L, Lally, J M, Martin, S R, O'Reilly, N J, Solomon, E, Freemont, P S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643677/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.4.1601
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