Arsenic-induced PML targeting onto nuclear bodies: Implications for the treatment of acute promyelocytic leukemia

Acute promyelocytic leukemia (APL) is associated with the t(15;17) translocation, which generates a PML/RARα fusion protein between PML, a growth suppressor localized on nuclear matrix-associated bodies, and RARα, a nuclear receptor for retinoic acid (RA). PML/RARα was proposed to block myeloid diff...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Zhu, Jun, Koken, Marcel H. M., Quignon, Frédérique, Chelbi-Alix, Mounira K., Degos, Laurent, Wang, Zhen Yi, Chen, Zhu, de Thé, Hugues
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1997
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20553/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108090/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.3978
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