Identification and preliminary characterization of protein-cysteine farnesyltransferase.
Ras proteins must be isoprenylated at a conserved cysteine residue near the carboxyl terminus (Cys-186 in mammalian Ras p21 proteins) in order to exert their biological activity. Previous studies indicate that an intermediate in the mevalonate pathway, most likely farnesyl pyrophosphate, is the dono...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54783/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2217184/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7541 |
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