Serotonin Signaling Through the 5-HT(1B) Receptor and NADPH Oxidase 1 in Pulmonary Arterial Hypertension

OBJECTIVE—: Serotonin can induce human pulmonary artery smooth muscle cell (hPASMC) proliferation through reactive oxygen species (ROS), influencing the development of pulmonary arterial hypertension (PAH). We hypothesize that in PASMCs, serotonin induces oxidative stress through NADPH-oxidase–deriv...

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Dades bibliogràfiques
Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Hood, Katie Y., Mair, Kirsty M., Harvey, Adam P., Montezano, Augusto C., Touyz, Rhian M., MacLean, Margaret R.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2017
Matèries:
Basic Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478178/
https://ncbi.nlm.nih.gov/pubmed/28473438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308929
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