Serotonin Signaling Through the 5-HT(1B) Receptor and NADPH Oxidase 1 in Pulmonary Arterial Hypertension

OBJECTIVE—: Serotonin can induce human pulmonary artery smooth muscle cell (hPASMC) proliferation through reactive oxygen species (ROS), influencing the development of pulmonary arterial hypertension (PAH). We hypothesize that in PASMCs, serotonin induces oxidative stress through NADPH-oxidase–deriv...

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Enregistré dans:
Détails bibliographiques
Publié dans:Arterioscler Thromb Vasc Biol
Auteurs principaux: Hood, Katie Y., Mair, Kirsty M., Harvey, Adam P., Montezano, Augusto C., Touyz, Rhian M., MacLean, Margaret R.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2017
Sujets:
Basic Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478178/
https://ncbi.nlm.nih.gov/pubmed/28473438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308929
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