Serotonin Signaling Through the 5-HT(1B) Receptor and NADPH Oxidase 1 in Pulmonary Arterial Hypertension

OBJECTIVE—: Serotonin can induce human pulmonary artery smooth muscle cell (hPASMC) proliferation through reactive oxygen species (ROS), influencing the development of pulmonary arterial hypertension (PAH). We hypothesize that in PASMCs, serotonin induces oxidative stress through NADPH-oxidase–deriv...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arterioscler Thromb Vasc Biol
Egile Nagusiak: Hood, Katie Y., Mair, Kirsty M., Harvey, Adam P., Montezano, Augusto C., Touyz, Rhian M., MacLean, Margaret R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Lippincott Williams & Wilkins 2017
Gaiak:
Basic Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478178/
https://ncbi.nlm.nih.gov/pubmed/28473438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308929
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