Nephropathy and Elevated BP in Mice with Podocyte-Specific NADPH Oxidase 5 Expression

NADPH oxidase (Nox) enzymes are a significant source of reactive oxygen species, which contribute to glomerular podocyte dysfunction. Although studies have implicated Nox1, -2, and -4 in several glomerulopathies, including diabetic nephropathy, little is known regarding the role of Nox5 in this cont...

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Main Authors: Holterman, Chet E., Thibodeau, Jean-François, Towaij, Chelsea, Gutsol, Alex, Montezano, Augusto C., Parks, Robin J., Cooper, Mark E., Touyz, Rhian M., Kennedy, Christopher R.J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2014
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968494/
https://ncbi.nlm.nih.gov/pubmed/24262797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013040371
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