Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma

PURPOSE: Proton magnetic resonance spectroscopy (MRS) of the brain can detect 2-hydroxyglutarate (2HG), the oncometabolite produced in neoplasms harboring a mutation in the gene coding for isocitrate dehydrogenase (IDH). We conducted a prospective longitudinal imaging study to determine whether quan...

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Опубликовано в: :J Clin Oncol
Главные авторы: Choi, Changho, Raisanen, Jack M., Ganji, Sandeep K., Zhang, Song, McNeil, Sarah S., An, Zhongxu, Madan, Akshay, Hatanpaa, Kimmo J., Vemireddy, Vamsidhara, Sheppard, Christie A., Oliver, Dwight, Hulsey, Keith M., Tiwari, Vivek, Mashimo, Tomoyuki, Battiste, James, Barnett, Samuel, Madden, Christopher J., Patel, Toral R., Pan, Edward, Malloy, Craig R., Mickey, Bruce E., Bachoo, Robert M., Maher, Elizabeth A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Clinical Oncology 2016
Предметы:
Original Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477829/
https://ncbi.nlm.nih.gov/pubmed/28248126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.67.1222
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