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A comparative study of short- and long-TE (1)H-MRS at 3T for in-vivo detection of 2-hydroxyglutarate in brain tumors
2-hydroxyglutarate (2HG) is produced in gliomas with mutations of isocitrate dehydrogenases (IDH) 1 and 2. The (1)H resonances of the J-coupled spins of 2HG are extensively overlapped with signals from other metabolites. Here we report a comparative study at 3T of the utility of the PRESS (point-res...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733061/ https://ncbi.nlm.nih.gov/pubmed/23592268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2943 |
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