A comparative study of short- and long-TE (1)H-MRS at 3T for in-vivo detection of 2-hydroxyglutarate in brain tumors

2-hydroxyglutarate (2HG) is produced in gliomas with mutations of isocitrate dehydrogenases (IDH) 1 and 2. The (1)H resonances of the J-coupled spins of 2HG are extensively overlapped with signals from other metabolites. Here we report a comparative study at 3T of the utility of the PRESS (point-res...

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Hlavní autoři: Choi, Changho, Ganji, Sandeep, Hulsey, Keith, Madan, Akshay, Kovacs, Zoltan, Dimitrov, Ivan, Zhang, Song, Pichumani, Kumar, Mendelsohn, Dianne, Mickey, Bruce, Malloy, Craig, Bachoo, Robert, DeBerardinis, Ralph, Maher, Elizabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733061/
https://ncbi.nlm.nih.gov/pubmed/23592268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2943
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