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Detection of 2-Hydroxyglutarate in Brain Tumors by Triple-Refocusing MRS at 3T In Vivo

PURPOSE: To test the efficacy of triple-refocusing MRS for improved detection of 2-hydroxyglutarate (2HG) in brain tumors at 3T in vivo. METHODS: The triple-refocusing sequence parameters were tailored at 3T, with density-matrix simulations and phantom validation, for enhancing the 2HG 2.25-ppm sign...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Magn Reson Med
Hauptverfasser: An, Zhongxu, Ganji, Sandeep K., Tiwari, Vivek, Pinho, Marco C., Patel, Toral, Barnett, Samuel, Pan, Edward, Mickey, Bruce E., Maher, Elizabeth A., Choi, Changho
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266748/
https://ncbi.nlm.nih.gov/pubmed/27454352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.26347
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