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In Vivo Detection of 2-Hydroxyglutarate in Brain Tumors by Optimized PRESS at 7T

PURPOSE: To test the efficacy of 7T MRS for in-vivo detection of 2-hydroxyglutarate (2HG) in brain tumors. METHODS: The subecho times of point-resolved spectroscopy (PRESS) were optimized at 7T, with density-matrix simulations and phantom validation, for improving the 2HG signal selectivity with res...

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Bibliographische Detailangaben
Veröffentlicht in:Magn Reson Med
Hauptverfasser: Ganji, Sandeep K., An, Zhongxu, Tiwari, Vivek, McNeil, Sarah, Pinho, Marco C., Pan, Edward, Mickey, Bruce E., Maher, Elizabeth A., Choi, Changho
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026542/
https://ncbi.nlm.nih.gov/pubmed/26991680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.26190
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