Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma

PURPOSE: Proton magnetic resonance spectroscopy (MRS) of the brain can detect 2-hydroxyglutarate (2HG), the oncometabolite produced in neoplasms harboring a mutation in the gene coding for isocitrate dehydrogenase (IDH). We conducted a prospective longitudinal imaging study to determine whether quan...

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Bibliographic Details
Published in:J Clin Oncol
Main Authors: Choi, Changho, Raisanen, Jack M., Ganji, Sandeep K., Zhang, Song, McNeil, Sarah S., An, Zhongxu, Madan, Akshay, Hatanpaa, Kimmo J., Vemireddy, Vamsidhara, Sheppard, Christie A., Oliver, Dwight, Hulsey, Keith M., Tiwari, Vivek, Mashimo, Tomoyuki, Battiste, James, Barnett, Samuel, Madden, Christopher J., Patel, Toral R., Pan, Edward, Malloy, Craig R., Mickey, Bruce E., Bachoo, Robert M., Maher, Elizabeth A.
Format: Artigo
Language:Inglês
Published: American Society of Clinical Oncology 2016
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Original Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477829/
https://ncbi.nlm.nih.gov/pubmed/28248126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.67.1222
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