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Single‐molecule imaging reveals the translocation and DNA looping dynamics of hepatitis C virus NS3 helicase

Non‐structural protein 3 (NS3) is an essential enzyme and a therapeutic target of hepatitis C virus (HCV). Compared to NS3‐catalyzed nucleic acids unwinding, its translation on single stranded nucleic acids have received relatively little attention. To investigate the NS3h translocation with single‐...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Lin, Chang‐Ting, Tritschler, Felix, Lee, Kyung Suk, Gu, Meigang, Rice, Charles M., Ha, Taekjip
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477530/
https://ncbi.nlm.nih.gov/pubmed/28176403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3136
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