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The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action

Genomic DNA replication requires helicases to processively unwind duplexes. Although helicases encoded by positive-strand RNA viruses are necessary for RNA genome replication, their functions are not well understood. We determined structures of the hepatitis C virus helicase (NS3h) in complex with t...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gu, Meigang, Rice, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938173/
https://ncbi.nlm.nih.gov/pubmed/27226535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704379
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