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RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP

Helicases are a ubiquitous class of enzymes involved in nearly all aspects of DNA and RNA metabolism. Despite recent progress in understanding their mechanism of action, limited resolution has left inaccessible the detailed mechanisms by which these enzymes couple the rearrangement of nucleic acid s...

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Detalhes bibliográficos
Main Authors: Dumont, Sophie, Cheng, Wei, Serebrov, Victor, Beran, Rudolf K., Tinoco, Ignacio, Pyle, Anna Marie, Bustamante, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560093/
https://ncbi.nlm.nih.gov/pubmed/16397502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04331
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