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RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP

Helicases are a ubiquitous class of enzymes involved in nearly all aspects of DNA and RNA metabolism. Despite recent progress in understanding their mechanism of action, limited resolution has left inaccessible the detailed mechanisms by which these enzymes couple the rearrangement of nucleic acid s...

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Autors principals: Dumont, Sophie, Cheng, Wei, Serebrov, Victor, Beran, Rudolf K., Tinoco, Ignacio, Pyle, Anna Marie, Bustamante, Carlos
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560093/
https://ncbi.nlm.nih.gov/pubmed/16397502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04331
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