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Hepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 Helicase
Non-structural protein 3 (NS3) is a multifunctional enzyme possessing serine protease, NTPase, and RNA unwinding activities that are required for hepatitis C viral (HCV) replication. HCV non-structural protein 4A (NS4A) binds to the N-terminal NS3 protease domain to stimulate NS3 serine protease act...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573085/ https://ncbi.nlm.nih.gov/pubmed/18723512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804065200 |
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