Visualizing ATP-dependent RNA Translocation by the NS3 Helicase from HCV

The structural mechanism by which non-structural protein 3 (NS3) from the hepatitis C virus (HCV) translocates along RNA is currently unknown. HCV NS3 is an ATP-dependent motor protein essential for viral replication and a member of the superfamily 2 (SF2) helicases. Crystallographic analysis using...

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Detalhes bibliográficos
Main Authors: Appleby, Todd C., Anderson, Robert, Fedorova, Olga, Pyle, Anna M., Wang, Ruth, Liu, Xiaohong, Brendza, Katherine M., Somoza, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134248/
https://ncbi.nlm.nih.gov/pubmed/21145896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.034
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