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Single-molecule analysis reveals differential effect of ssDNA-binding proteins on DNA translocation by XPD helicase

An encounter between a DNA translocating enzyme and a DNA-bound protein must occur frequently in the cell but little is known about its outcome. Here, we developed a multi-color single molecule fluorescence approach to simultaneously monitor single stranded (ss) DNA translocation by a helicase and t...

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Detalhes bibliográficos
Main Authors: Honda, Masayoshi, Park, Jeehae, Pugh, Robert A., Ha, Taekjip, Spies, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776038/
https://ncbi.nlm.nih.gov/pubmed/19748362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.003
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