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DNA translocation mechanism of an XPD family helicase
The XPD family of helicases, that includes human disease-related FANCJ, DDX11 and RTEL1, are Superfamily two helicases that contain an iron-sulphur cluster domain, translocate on ssDNA in a 5’−3’ direction and play important roles in genome stability. Consequently, mutations in several of these fami...
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Publicado no: | eLife |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6300356/ https://ncbi.nlm.nih.gov/pubmed/30520735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42400 |
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