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DNA translocation mechanism of an XPD family helicase

The XPD family of helicases, that includes human disease-related FANCJ, DDX11 and RTEL1, are Superfamily two helicases that contain an iron-sulphur cluster domain, translocate on ssDNA in a 5’−3’ direction and play important roles in genome stability. Consequently, mutations in several of these fami...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Cheng, Kaiying, Wigley, Dale B
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300356/
https://ncbi.nlm.nih.gov/pubmed/30520735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42400
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