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Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism
DNA footprinting and nuclease protection studies of PcrA helicase complexed with a 3′-tailed DNA duplex reveal a contact region that covers a significant region of the substrate both in the presence and absence of a non-hydrolysable analogue of ATP, ADPNP. However, details of the interactions of the...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.14.3799 |
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