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Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism
DNA footprinting and nuclease protection studies of PcrA helicase complexed with a 3′-tailed DNA duplex reveal a contact region that covers a significant region of the substrate both in the presence and absence of a non-hydrolysable analogue of ATP, ADPNP. However, details of the interactions of the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313991/ https://ncbi.nlm.nih.gov/pubmed/10899133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3799 |
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