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Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism
DNA footprinting and nuclease protection studies of PcrA helicase complexed with a 3′-tailed DNA duplex reveal a contact region that covers a significant region of the substrate both in the presence and absence of a non-hydrolysable analogue of ATP, ADPNP. However, details of the interactions of the...
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| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.14.3799 |
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