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Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism

DNA footprinting and nuclease protection studies of PcrA helicase complexed with a 3′-tailed DNA duplex reveal a contact region that covers a significant region of the substrate both in the presence and absence of a non-hydrolysable analogue of ATP, ADPNP. However, details of the interactions of the...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Soultanas, Panos, Dillingham, Mark S., Wiley, Paul, Webb, Martin R., Wigley, Dale B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313991/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899133/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.14.3799
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