Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement

BACKGROUND: Natural IgM antibodies (Abs) function as innate immune sensors of injury via recognition of neoepitopes expressed on damaged cells, although how this recognition systems function following spinal cord injury (SCI) exposes various neoepitopes and their precise nature remains largely unkno...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neuroinflammation
Egile Nagusiak: Narang, Aarti, Qiao, Fei, Atkinson, Carl, Zhu, Hong, Yang, Xiaofeng, Kulik, Liudmila, Holers, V. Michael, Tomlinson, Stephen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477255/
https://ncbi.nlm.nih.gov/pubmed/28629465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0894-6
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