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Targeting Pathogenic Post-Ischemic Self-Recognition by Natural IgM to Protect Against Post-Transplant Cardiac Reperfusion Injury

BACKGROUND: Natural IgM antibodies represent a class of innate pattern recognition receptors that recognize danger associated molecular patterns expressed on stressed or dying cells. They play important roles in tissue homeostasis by disposing of pre-necrotic cells and suppressing inflammation. Howe...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Atkinson, Carl, Qiao, Fei, Yang, Xiaofeng, Zhu, Peng, Reaves, Nicholas, Kulik, Liudmila, Goddard, Martin, Holers, V. Michael, Tomlinson, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382916/
https://ncbi.nlm.nih.gov/pubmed/25825397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.010482
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