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Efficient Total Chemical Synthesis of (13)C=(18)O Isotopomers of Human Insulin for Isotope-Edited FTIR

Isotope-edited two-dimensional Fourier transform infrared spectroscopy (2D FTIR) can potentially provide a unique probe of protein structure and dynamics. However, general methods for the site-specific incorporation of stable (13)C=(18)O labels into the polypeptide backbone of the protein molecule h...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Dhayalan, Balamurugan, Fitzpatrick, Ann, Mandal, Kalyaneswar, Whittaker, Jonathan, Weiss, Michael A., Tokmakoff, Andrei, Kent, Stephen B. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477233/
https://ncbi.nlm.nih.gov/pubmed/26715336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500601
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