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Refinement of Peptide Conformational Ensembles by 2D IR Spectroscopy: Application to Ala‒Ala‒Ala

Characterizing ensembles of intrinsically disordered proteins is experimentally challenging because of the ill-conditioned nature of ensemble determination with limited data and the intrinsic fast dynamics of the conformational ensemble. Amide I two-dimensional infrared (2D IR) spectroscopy has pico...

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Pubblicato in:Biophys J
Autori principali: Feng, Chi-Jui, Dhayalan, Balamurugan, Tokmakoff, Andrei
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026468/
https://ncbi.nlm.nih.gov/pubmed/29925019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.05.003
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