The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models

Spinocerebellar ataxia type 3 (SCA3), known as Machado-Joseph disease, is an autosomal dominant disease caused by an abnormal expansion of polyglutamine in ATXN3 gene, leading to neurodegeneration in SCA3 patients. Similar to other neurodegenerative diseases, the dysfunction of mitochondria is obser...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Mol Neurosci
Päätekijät: Hsu, Jung-Yu, Jhang, Yu-Ling, Cheng, Pei-Hsun, Chang, Yu-Fan, Mao, Su-Han, Yang, Han-In, Lin, Chia-Wei, Chen, Chuan-Mu, Yang, Shang-Hsun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2017
Aiheet:
Neuroscience
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476786/
https://ncbi.nlm.nih.gov/pubmed/28676741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00196
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia