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Error-Prone Replication Bypass of the Imidazole Ring-Opened Formamidopyrimidine Deoxyguanosine Adduct
Addition of hydroxyl radicals to the C8 position of 2′-deoxyguanosine generates an 8-hydroxyguanyl radical that can be converted into either 8-oxo-7,8-dihydro-2′-deoxyguanosine or N-(2-deoxy-D-pentofuranosyl)-N-(2,6-diamino-4-hydroxy-5-formamidopyrimidine) (Fapy-dG). The Fapy-dG adduct can adopt dif...
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| Publicado no: | Environ Mol Mutagen |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5476229/ https://ncbi.nlm.nih.gov/pubmed/28436537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22089 |
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