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Replication Past the N(5)-Methyl-Formamidopyrimidine Lesion of Deoxyguanosine by DNA Polymerases and an Improved Procedure for Sequence Analysis of In Vitro Bypass Products by Mass Spectrometry
Oligonucleotides containing a site-specific N(6)-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine (MeFapy-dGuo) lesion were synthesized and their in vitro replication by Escherichia coli DNA polymerase I Klenow fragment (exo(−)) and Sulfolobus solfataric...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754150/ https://ncbi.nlm.nih.gov/pubmed/19397282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900047c |
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