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Replication Past the N(5)-Methyl-Formamidopyrimidine Lesion of Deoxyguanosine by DNA Polymerases and an Improved Procedure for Sequence Analysis of In Vitro Bypass Products by Mass Spectrometry

Oligonucleotides containing a site-specific N(6)-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine (MeFapy-dGuo) lesion were synthesized and their in vitro replication by Escherichia coli DNA polymerase I Klenow fragment (exo(−)) and Sulfolobus solfataric...

詳細記述

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書誌詳細
主要な著者: Christov, Plamen P., Angel, Karen C., Guengerich, F. Peter, Rizzo, Carmelo J.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754150/
https://ncbi.nlm.nih.gov/pubmed/19397282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900047c
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