Endoplasmic Reticulum Stress Sensor IRE1α Enhances IL-23 Expression by Human Dendritic Cells

Human monocyte-derived dendritic cells (DCs) exposed to pathogen-associated molecular patterns (PAMPs) undergo bioenergetic changes that influence the immune response. We found that stimulation with PAMPs enhanced glycolysis in DCs, whereas oxidative phosphorylation remained unaltered. Glucose starv...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Márquez, Saioa, Fernández, José Javier, Terán-Cabanillas, Eli, Herrero, Carmen, Alonso, Sara, Azogil, Alicia, Montero, Olimpio, Iwawaki, Takao, Cubillos-Ruiz, Juan R., Fernández, Nieves, Crespo, Mariano Sánchez
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475432/
https://ncbi.nlm.nih.gov/pubmed/28674530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00639
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