TMOD-05. MOLECULAR CHARACTERIZATION OF ORTHOTOPIC PATIENT-DERIVED XENOGRAFT MODELS OF PEDIATRIC BRAIN TUMORS AND THEIR USE IN PRECLINICAL EXPERIMENTS

Genomic studies have shown that multiple molecular subtypes of pediatric brain tumors exist that are biologically and clinically highly distinct. These findings ask for novel subtype specific treatments. To develop these we need more and better preclinical models that correctly reflect the proper tu...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Brabetz, Sebastian, Schmidt, Christin, Groebner, Susanne N., Mack, Norman, Seker-Cin, Huriye, Jones, David T.W., Chavez, Lukas, Milde, Till, Witt, Olaf, Leary, Sarah E., Li, Xiao-Nan, Wechsler-Reya, Robert J., Olson, James M., Pfister, Stefan M., Kool, Marcel
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Abstracts
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475173/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.204
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