MBRS-33. RNA-SEQUENCING OF MEDULLOBLASTOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS ENABLES IDENTIFICATION OF BOTH TUMOR AND MICROENVIRONMENT SPECIFIC BIOMARKERS

Therapies for medulloblastoma, a highly malignant pediatric brain tumor, often impose debilitating effects on the developing child, highlighting the need for molecularly targeted treatments with reduced toxicity. Therapies aimed at tumor-intrinsic mechanisms have translated to limited success thus f...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Jäger, Natalie, Brabetz, Sebastian, Pfister, Stefan, Kool, Marcel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012086/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.478
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