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CADD-33. PERSONALIZED PHARMACOGENOMICS USING GLIOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS (PDOXS)

It is well recognized that long term cell cultures are poor models to study human cancer, largely because of loss of clonal heterogeneity, accumulation or loss of genomic alterations and adaptation to a highly artificial environment. Patient-derived orthotopic xenografts (PDOX) based on organotypic...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hau, Ann-Christin, Golebiewska, Anna, Oudin, Anaïs, Houben, Linsey, Stieber, Daniel, Hertel, Frank, Niclou, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216873/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1173
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