CADD-33. PERSONALIZED PHARMACOGENOMICS USING GLIOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS (PDOXS)

It is well recognized that long term cell cultures are poor models to study human cancer, largely because of loss of clonal heterogeneity, accumulation or loss of genomic alterations and adaptation to a highly artificial environment. Patient-derived orthotopic xenografts (PDOX) based on organotypic...

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Publicado en:Neuro Oncol
Autores principales: Hau, Ann-Christin, Golebiewska, Anna, Oudin, Anaïs, Houben, Linsey, Stieber, Daniel, Hertel, Frank, Niclou, Simone
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216873/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1173
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