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P04.64 Molecular characterization of glioma patient derived orthotopic xenografts to improve outcome of preclinical studies
BACKGROUND: It is well recognized that long term cell cultures are poor models to study human cancer, largely because of loss of clonal heterogeneity, accumulation or loss of genomic alterations and adaptation to a highly artificial environment. Patient-derived orthotopic xenografts (PDOX) based on...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6144237/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.298 |
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