P04.64 Molecular characterization of glioma patient derived orthotopic xenografts to improve outcome of preclinical studies

BACKGROUND: It is well recognized that long term cell cultures are poor models to study human cancer, largely because of loss of clonal heterogeneity, accumulation or loss of genomic alterations and adaptation to a highly artificial environment. Patient-derived orthotopic xenografts (PDOX) based on...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Golebiewska, A, Hau, A, Oudin, A, Houben, L, Stieber, D, Azuaje, F, Kaony, T, Muller, A, Hertel, F, Mittelbronn, M, Bjerkvig, R, Niclou, S P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Poster Presentations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144237/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.298
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