P04.64 Molecular characterization of glioma patient derived orthotopic xenografts to improve outcome of preclinical studies

BACKGROUND: It is well recognized that long term cell cultures are poor models to study human cancer, largely because of loss of clonal heterogeneity, accumulation or loss of genomic alterations and adaptation to a highly artificial environment. Patient-derived orthotopic xenografts (PDOX) based on...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Golebiewska, A, Hau, A, Oudin, A, Houben, L, Stieber, D, Azuaje, F, Kaony, T, Muller, A, Hertel, F, Mittelbronn, M, Bjerkvig, R, Niclou, S P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Poster Presentations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144237/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.298
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