PCLN-05. A BIOBANK OF PATIENT-DERIVED MOLECULARLY CHARACTERIZED ORTHOTOPIC PEDIATRIC BRAIN TUMOR MODELS FOR PRECLINICAL RESEARCH

Identification of multiple distinct subtypes of pediatric brain tumors raises the need for more and better preclinical models reflecting these subtypes. Orthotopic patient-derived xenograft (PDX) models generated by injection of human tumor cells into the brain of NSG mice offer the unique possibili...

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Publicat a:Neuro Oncol
Autors principals: Brabetz, Sebastian, Groebner, Susanne N, Jaeger, Natalie, Milde, Till, Ecker, Jonas, Selt, Florian, Witt, Olaf, Rusert, Jessica M, Koster, Jan, Leary, Sarah E, Li, Xiao-Nan, Wechsler-Reya, Robert J, Olson, James M, Pfister, Stefan M, Kool, Marcel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012525/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.574
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