PCLN-05. A BIOBANK OF PATIENT-DERIVED MOLECULARLY CHARACTERIZED ORTHOTOPIC PEDIATRIC BRAIN TUMOR MODELS FOR PRECLINICAL RESEARCH

Identification of multiple distinct subtypes of pediatric brain tumors raises the need for more and better preclinical models reflecting these subtypes. Orthotopic patient-derived xenograft (PDX) models generated by injection of human tumor cells into the brain of NSG mice offer the unique possibili...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Brabetz, Sebastian, Groebner, Susanne N, Jaeger, Natalie, Milde, Till, Ecker, Jonas, Selt, Florian, Witt, Olaf, Rusert, Jessica M, Koster, Jan, Leary, Sarah E, Li, Xiao-Nan, Wechsler-Reya, Robert J, Olson, James M, Pfister, Stefan M, Kool, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012525/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.574
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