TMOD-05. MOLECULAR CHARACTERIZATION OF ORTHOTOPIC PATIENT-DERIVED XENOGRAFT MODELS OF PEDIATRIC BRAIN TUMORS AND THEIR USE IN PRECLINICAL EXPERIMENTS

Genomic studies have shown that multiple molecular subtypes of pediatric brain tumors exist that are biologically and clinically highly distinct. These findings ask for novel subtype specific treatments. To develop these we need more and better preclinical models that correctly reflect the proper tu...

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Pubblicato in:Neuro Oncol
Autori principali: Brabetz, Sebastian, Schmidt, Christin, Groebner, Susanne N., Mack, Norman, Seker-Cin, Huriye, Jones, David T.W., Chavez, Lukas, Milde, Till, Witt, Olaf, Leary, Sarah E., Li, Xiao-Nan, Wechsler-Reya, Robert J., Olson, James M., Pfister, Stefan M., Kool, Marcel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475173/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.204
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